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Other established ED treatments include: Vacuum erection devices Intracavernosal injections (alprostadil) Intraurethral alprostadil Testosterone replacement (for confirmed hypogonadism) Psychosexual therapy Penile prosthesis surgery (for refractory cases) All of these options have defined roles in ED management and are supported by clinical evidence

Specifically, researchers have engineered EcN to express a nitrate-responsive promoter and a luciferase gene cluster, enabling the bacteria to emit light actively in an inflammatory environment

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Biochemical Society Transactions